Bromelain for Dogs: What It Does and Why It Matters

Bromelain is a group of proteolytic enzymes from pineapple stem. In canine supplements, it serves two roles: enhancing absorption of quercetin and other polyphenols, and providing independent anti-inflammatory activity through prostaglandin suppression and fibrin degradation.

Bromelain's mechanisms

• Quercetin bioavailability enhancement: Increases quercetin absorption 3–10x — without this, most quercetin passes through unabsorbed
• Prostaglandin E2 inhibition: Reduces arachidonic acid release, lowering prostaglandin synthesis that drives inflammation, pain, and vascular permeability
• Fibrin degradation: Breaks down excess fibrin in inflamed tissue, reducing local swelling in ear canals, skin folds, and joints
• T cell modulation: Reduces CD44 expression on T helper cells, shifting immune responses away from Th2 allergic polarization

Dosing

Typically 50–250mg depending on dog weight, combined with quercetin. Measured in GDU (gelatin digesting units) — 500 GDU/g is a reasonable minimum activity standard. Take on empty stomach for maximum immune effect, or with food if GI sensitivity occurs.

Who benefits most

Dogs with chronic allergy, recurring ear infections, skin fold inflammation, post-surgical swelling, and digestive sensitivity all benefit from bromelain. It is safe for long-term daily use.